The protein encoded by the Arabidopsis homeotic gene agamous resembles transcription factors

Nature. 1990 Jul 5;346(6279):35-9. doi: 10.1038/346035a0.


Mutations in the homeotic gene agamous of the plant Arabidopsis cause the transformation of the floral sex organs. Cloning and sequence analysis of agamous suggest that it encodes a protein with a high degree of sequence similarity to the DNA-binding region of transcription factors from yeast and humans and to the product of a homeotic gene from Antirrhinum. The agamous gene therefore probably encodes a transcription factor that regulates genes determining stamen and carpel development in wild-type flowers.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Base Sequence
  • Blotting, Northern
  • Cloning, Molecular
  • Gene Expression
  • Genes, Homeobox*
  • Genes, Plant*
  • Molecular Sequence Data
  • Morphogenesis
  • Nucleic Acid Hybridization
  • Plants / genetics*
  • Polymorphism, Restriction Fragment Length
  • Restriction Mapping
  • Transcription Factors / genetics*


  • Transcription Factors

Associated data

  • GENBANK/X53579