Abstract
Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC) is used for selected gastrointestinal carcinomas. We report a case of ventricular tachycardia during HIPEC with cisplatin that persisted as long as the chemotherapy solution remained in the intra-abdominal cavity. We hypothesise that high plasma levels of cisplatin with concomitant low magnesium levels caused the arrhythmia.
MeSH terms
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Aged
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Antineoplastic Agents / administration & dosage
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Antineoplastic Agents / adverse effects*
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Chemotherapy, Adjuvant
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Cisplatin / administration & dosage
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Cisplatin / adverse effects*
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Female
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Humans
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Hyperthermia, Induced
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Infusions, Parenteral
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Peritoneal Neoplasms / drug therapy*
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Peritoneal Neoplasms / secondary
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Peritoneal Neoplasms / surgery
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Tachycardia, Ventricular / chemically induced*
Substances
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Antineoplastic Agents
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Cisplatin