A novel LCD (coal tar) solution for psoriasis does not discolor naturally light or color-processed hair in an exaggerated exposure test model

J Cosmet Dermatol. 2009 Sep;8(3):211-5. doi: 10.1111/j.1473-2165.2009.00453.x.

Abstract

Background: Scalp psoriasis is reported to occur in 50-80% of psoriasis sufferers. Treatment of scalp psoriasis requires special consideration of product esthetics and staining potential due to the presence of hair.

Aim: To evaluate the potential of a new, marketed liquor carbonis distillate (LCD; coal tar) solution to discolor naturally light or color-processed hair under exaggerated exposure conditions.

Methods: Samples of naturally light and color-processed hair from a single donor were exposed to LCD solution repeatedly over 14 days and via submergence for 24 h. Color of LCD-treated hair samples was compared with untreated control hair samples.

Results: LCD solution did not discolor naturally light or color-processed hair following repeated exposures and 24 h submergence.

Conclusion: The marketed LCD solution does not appear to discolor naturally light or color-processed hair.

MeSH terms

  • Coal Tar / therapeutic use*
  • Hair / drug effects*
  • Hair Color / drug effects*
  • Hair Dyes / pharmacology
  • Humans
  • Psoriasis / drug therapy*
  • Scalp / drug effects*

Substances

  • Hair Dyes
  • Coal Tar