Primary cutaneous aspergillosis due to Aspergillus niger in an immunocompetent patient

Indian J Med Microbiol. 2009 Oct-Dec;27(4):367-70. doi: 10.4103/0255-0857.55462.

Abstract

Primary cutaneous aspergillosis is a rare entity, usually caused by A. fumigatus and A. flavus . Here, we present such a case, manifested by ulceration due to A. niger, which remained undiagnosed for a prolonged period. The immunological status was intact, although the patient had associated severe fungal infection. Recurrence of the lesion occurred despite repeated anti-fungal therapies. Anti fungal testing was done based on the broth dilution (M-38A, NCCLS, USA) method. The culture isolate was found to be sensitive to fluconazole and amphotericin B. Continuation of antifungal therapy improved the symptoms, reducing the size of the lesion.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antifungal Agents / pharmacology
  • Antifungal Agents / therapeutic use
  • Aspergillosis / diagnosis*
  • Aspergillosis / pathology
  • Aspergillosis / physiopathology
  • Aspergillus niger / isolation & purification*
  • Dermatomycoses / diagnosis*
  • Dermatomycoses / pathology
  • Dermatomycoses / physiopathology
  • Humans
  • Male
  • Microbial Sensitivity Tests
  • Recurrence
  • Skin Ulcer / microbiology
  • Skin Ulcer / pathology

Substances

  • Antifungal Agents