The Rea1 tadpole loses its tail

Cell. 2009 Sep 4;138(5):832-4. doi: 10.1016/j.cell.2009.08.019.


More than 170 assembly factors aid the construction and maturation of yeast ribosomes. After these factors' functions are completed, they must be released from preribosomes. In this issue, Ulbrich et al. (2009) describe a mechanochemical process through which the AAA ATPase Rea1 induces release of an assembly protein complex from preribosomes.

Publication types

  • Comment

MeSH terms

  • ATPases Associated with Diverse Cellular Activities
  • Adenosine Triphosphatases / chemistry
  • Adenosine Triphosphatases / metabolism*
  • Nuclear Proteins / metabolism
  • Ribosomes / metabolism*
  • Saccharomyces cerevisiae / metabolism*
  • Saccharomyces cerevisiae Proteins / chemistry
  • Saccharomyces cerevisiae Proteins / metabolism*


  • Nuclear Proteins
  • Saccharomyces cerevisiae Proteins
  • Adenosine Triphosphatases
  • MDN1 protein, S cerevisiae
  • ATPases Associated with Diverse Cellular Activities