Cellular and Molecular Mechanisms Underlying the Formation of Biological Tubes

Curr Top Dev Biol. 2009;89:137-62. doi: 10.1016/S0070-2153(09)89006-6.


Biological tubes are integral components of many organs. Based on their cellular organization, tubes can be divided into three types: multicellular, unicellular, and intracellular. The mechanisms by which these tubes form during development vary significantly, in many cases even for those sharing a similar final architecture. Here, we present recent advances in studying cellular and molecular aspects of tubulogenesis in different organisms.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Cell Physiological Phenomena
  • Humans
  • Organogenesis*