A case report of rapid progressive coarctation and severe middle aortic syndrome in an infant with Williams syndrome

Congenit Heart Dis. 2009 Sep-Oct;4(5):373-7. doi: 10.1111/j.1747-0803.2009.00287.x.

Abstract

Williams syndrome is a genetic disorder caused by multiple contiguous gene deletions in chromosome 7. Presentation in early life is most often a result of luminal stenosis of right- and left-sided arterial vasculature. We report the case of a newborn infant who had a rapidly progressing diffuse form of arteriopathy that required two surgeries and one percutaneous balloon dilation within the first 2 months of her life.

Publication types

  • Case Reports

MeSH terms

  • Angioplasty, Balloon*
  • Aortic Coarctation / diagnosis
  • Aortic Coarctation / genetics
  • Aortic Coarctation / surgery
  • Aortic Coarctation / therapy*
  • Aortic Diseases / diagnosis
  • Aortic Diseases / genetics
  • Aortic Diseases / surgery
  • Aortic Diseases / therapy*
  • Arterial Occlusive Diseases / diagnosis
  • Arterial Occlusive Diseases / genetics
  • Arterial Occlusive Diseases / surgery
  • Arterial Occlusive Diseases / therapy*
  • Constriction, Pathologic
  • Disease Progression
  • Female
  • Humans
  • Infant, Newborn
  • Severity of Illness Index
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Vascular Surgical Procedures*
  • Williams Syndrome / complications*
  • Williams Syndrome / diagnosis
  • Williams Syndrome / genetics
  • Williams Syndrome / therapy