Coexisting NRAS and BRAF mutations in primary familial melanomas with specific CDKN2A germline alterations

J Invest Dermatol. 2010 Feb;130(2):618-20. doi: 10.1038/jid.2009.287. Epub 2009 Sep 17.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Cyclin-Dependent Kinase Inhibitor p16 / biosynthesis
  • Cyclin-Dependent Kinase Inhibitor p16 / genetics*
  • Family Health
  • Female
  • Gene Expression Regulation, Neoplastic*
  • Germ-Line Mutation*
  • Humans
  • Male
  • Melanoma / genetics*
  • Middle Aged
  • Mutation*
  • Proto-Oncogene Proteins B-raf / biosynthesis
  • Proto-Oncogene Proteins B-raf / genetics*
  • Skin Neoplasms / genetics*
  • ras Proteins / biosynthesis
  • ras Proteins / genetics*

Substances

  • Cyclin-Dependent Kinase Inhibitor p16
  • BRAF protein, human
  • Proto-Oncogene Proteins B-raf
  • ras Proteins