CanGeneBase (CGB)--a database on cancer related genes

Bioinformation. 2009 Jul 27;3(10):422-4. doi: 10.6026/97320630003422.

Abstract

The advent of genomic and proteomic technologies in this post-genomic era has urged the researchers to develop novel research strategies against cancer by targeting the human genes that would greatly facilitate to identify more promising treatment and to develop accurate early diagnosis for cancer. To harness the power of cancer genetic information towards better treatment we have developed a cancer gene database called CanGeneBase (CGB). It is a comprehensive data collection of cancer-related genes with the intention of helping the researchers to stay on a single platform to gain exclusive information on the genes of their interest. According to the Cancer Gene Data Curation Project, about 4,700 genes have been identified as being related to cancer. The present CanGeneBase covers about 12 different types of cancer which includes 190 unique gene entries. Each entry encompasses about 33 useful parameters to provide detailed information about specific gene. CanGeneBase is made in such a way that it can be easily accessed by either gene symbol or by the type of cancer.

Availability: The database is freely available at http://122.165.25.137/bioinfo/cancerdb/

Keywords: Cancer; cancer types; database; drug list; molecular descriptors; oncogenes; target; tumour suppressor genes.