Preparation and bioapplication of high-quality, water-soluble, biocompatible, and near-infrared-emitting CdSeTe alloyed quantum dots

Nanotechnology. 2009 Oct 14;20(41):415103. doi: 10.1088/0957-4484/20/41/415103. Epub 2009 Sep 18.

Abstract

A facile method is developed for the preparation of high-quality, water-soluble, and near-infrared (NIR)-emitting CdSeTe alloyed quantum dots (AQdots) with L-cysteine as the capping agent. By changing the size and the composition of AQdots the photoluminescent quantum yield (QY) can reach as high as 53% and the emission color can be tuned between visible and NIR regions (580-814 nm). Furthermore, the prepared NIR-emitting AQdots have been successfully applied for HL-60 cell imaging and glucose and cholesterol assay, which demonstrates the great potential of the AQdots for biological applications.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alloys / chemical synthesis
  • Alloys / chemistry*
  • Cadmium / chemistry*
  • Diagnostic Imaging / methods*
  • HL-60 Cells
  • Humans
  • Nanotechnology / methods*
  • Quantum Dots*
  • Selenium / chemistry*
  • Tellurium / chemistry*

Substances

  • Alloys
  • Cadmium
  • Selenium
  • Tellurium