Oxidative carboxylation of arylaldehydes with water by a sulfoxylalkyl-substituted N-heterocyclic carbene catalyst

Org Biomol Chem. 2009 Oct 7;7(19):4062-6. doi: 10.1039/b910187j. Epub 2009 Jul 31.

Abstract

The N-Heterocyclic carbene-catalysed oxidative carboxylation of arylaldehydes with water successfully proceeded when a sulfoxylalkyl-substituted imidazolium salt was used as the catalyst. The reactions can be run in the absence of oxidant, and a variety of arylaldehydes having an electron-withdrawing group were converted to the corresponding carboxylic acids.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aldehydes / chemistry*
  • Carboxylic Acids / chemistry*
  • Catalysis
  • Imidazoles / chemistry*
  • Methane / analogs & derivatives*
  • Methane / chemistry
  • Oxidation-Reduction
  • Water / chemistry*

Substances

  • Aldehydes
  • Carboxylic Acids
  • Imidazoles
  • Water
  • carbene
  • imidazole
  • Methane