Translating inflammatory bowel disease research into clinical medicine

Immunity. 2009 Sep 18;31(3):357-61. doi: 10.1016/j.immuni.2009.08.016.


Recent studies have provided important insights into the pathogenesis of inflammatory bowel disease (IBD). The development of new therapeutic agents has been triggered by basic research and studies in mouse models of IBD. It is expected that improved translational research will lead to optimized therapy and new individualized treatment options.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anti-Inflammatory Agents / therapeutic use*
  • CD4-Positive T-Lymphocytes / immunology
  • Disease Models, Animal
  • Drug Discovery*
  • Humans
  • Inflammatory Bowel Diseases / drug therapy*
  • Inflammatory Bowel Diseases / etiology
  • Inflammatory Bowel Diseases / immunology
  • Interleukins / immunology
  • Mononuclear Phagocyte System / immunology


  • Anti-Inflammatory Agents
  • Interleukins