A longitudinal comparison of body composition changes in adolescent girls receiving hormonal contraception

J Adolesc Health. 2009 Oct;45(4):423-5. doi: 10.1016/j.jadohealth.2009.04.009. Epub 2009 Jun 21.


The objective of this study was to examine body composition changes in adolescent girls initiating depot medroxyprogesterone acetate (DMPA), oral contraceptives, or no hormonal contraceptive method. At 6 months, DMPA resulted in significant increases in adiposity with concomitant decreases in lean body mass. Supplemental estrogen may lessen these DMPA effects.

Publication types

  • Comparative Study
  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Body Composition / drug effects*
  • Body Mass Index
  • Bone Density
  • Child
  • Contraceptives, Oral*
  • Delayed-Action Preparations
  • Female
  • Humans
  • Longitudinal Studies


  • Contraceptives, Oral
  • Delayed-Action Preparations