Structural insights into Staphylococcus aureus enoyl-ACP reductase (FabI), in complex with NADP and triclosan

Proteins. 2010 Feb 1;78(2):480-6. doi: 10.1002/prot.22581.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Infective Agents, Local / chemistry
  • Anti-Infective Agents, Local / pharmacology*
  • Crystallography, X-Ray
  • Enoyl-(Acyl-Carrier-Protein) Reductase (NADH) / chemistry*
  • Enoyl-(Acyl-Carrier-Protein) Reductase (NADH) / metabolism*
  • Models, Molecular
  • NADP / chemistry
  • NADP / metabolism*
  • Protein Binding
  • Protein Conformation
  • Staphylococcus aureus / enzymology*
  • Triclosan / chemistry
  • Triclosan / pharmacology*

Substances

  • Anti-Infective Agents, Local
  • Triclosan
  • NADP
  • Enoyl-(Acyl-Carrier-Protein) Reductase (NADH)