Antenatal intervention for congenital cystic adenomatoid malformation

Lancet. 1990 Oct 20;336(8721):965-7. doi: 10.1016/0140-6736(90)92420-m.


In 2 fetuses with congenital cystic adenomatoid malformation (CCAM) with hydrops, in-utero resection of the enlarged pulmonary lobe reduced mediastinal shift and allowed expansion of normal lung tissue in both cases. In case 1, the 27-week-gestation fetus died from severe hydrops after premature delivery. In case 2, fetal CCAM resection was completed at 23 weeks' gestation. At 30 weeks a girl was delivered with no evidence of pulmonary hypoplasia. Fetal surgery can now be entertained for otherwise fatal space-occupying intrathoracic lesions.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cystic Adenomatoid Malformation of Lung, Congenital / diagnosis
  • Cystic Adenomatoid Malformation of Lung, Congenital / surgery*
  • Evaluation Studies as Topic
  • Female
  • Fetal Diseases / diagnosis
  • Fetal Diseases / surgery*
  • Fetal Monitoring
  • Gestational Age
  • Humans
  • Hydrops Fetalis / complications
  • Infant, Newborn
  • Infant, Premature*
  • Pregnancy
  • Prognosis
  • Ultrasonography, Prenatal