NMR assignments of the FK506-binding domain of FK506-binding protein 35 from Plasmodium vivax

Biomol NMR Assign. 2009 Dec;3(2):243-5. doi: 10.1007/s12104-009-9185-1.


PvFKBP35 is a member of the FK506 binding protein family (FKBP) from Plasmodium vivax. The FK506-binding domain of PvFKBP35 shows a canonical peptidylprolyl cis-trans isomerase (PPIase) activity. To understand the role of PvFKBP35 in the parasite, we have performed NMR studies. Here, we report the assignment of the FK506-binding domain of PvFKBP35.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Antimalarials
  • Drug Design
  • Humans
  • Molecular Sequence Data
  • Nuclear Magnetic Resonance, Biomolecular
  • Plasmodium vivax*
  • Protein Structure, Tertiary
  • Protozoan Proteins / chemistry*
  • Protozoan Proteins / metabolism*
  • Tacrolimus / metabolism*


  • Antimalarials
  • Protozoan Proteins
  • Tacrolimus