A novel HLA-DRB1 allele, DRB1*112802, was identified in a Chinese individual

Tissue Antigens. 2009 Oct;74(4):350-2. doi: 10.1111/j.1399-0039.2009.01329.x.

Abstract

We report here a novel human leukocyte antigen-DRB1 allele, DRB1*112802, which was identified from a Chinese individual during sequence-based typing. The new allele is identical to DRB1*112801 except for one nucleotide change at nucleotide 189 (A --> G ), codon 34 Q (CAA) --> Q (CAG), no coding change.

MeSH terms

  • Alleles
  • Amino Acid Sequence
  • Amino Acid Substitution
  • Asian People / genetics
  • Base Sequence
  • HLA-DR Antigens / blood
  • HLA-DR Antigens / genetics*
  • HLA-DRB1 Chains
  • Humans
  • Molecular Sequence Data
  • Polymerase Chain Reaction
  • Sequence Analysis, DNA*
  • Sequence Homology, Amino Acid
  • Sequence Homology, Nucleic Acid

Substances

  • HLA-DR Antigens
  • HLA-DRB1 Chains