Cortical enlightenment: are attentional gamma oscillations driven by ING or PING?

Neuron. 2009 Sep 24;63(6):727-32. doi: 10.1016/j.neuron.2009.09.009.


The response of a neuron to sensory stimuli can only give correlational support for functional hypotheses. To experimentally test causal function, the neural activity needs to be manipulated in a cell-type-specific as well as spatially and temporally precise way. We review recent optogenetic experiments on parvalbumin-positive cortical interneurons that link modeling studies of synchronization to experimental studies on attentional modulation of gamma oscillations in primates.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Animals
  • Attention / physiology*
  • Biological Clocks / physiology*
  • Cerebral Cortex / cytology*
  • Humans
  • Interneurons / physiology*
  • Models, Neurological
  • Nerve Net / physiology
  • Neural Inhibition / physiology
  • Neural Pathways / physiology
  • Space Perception / physiology*