Coffee consumption and risk of heart failure in men: an analysis from the Cohort of Swedish Men

Am Heart J. 2009 Oct;158(4):667-72. doi: 10.1016/j.ahj.2009.07.006. Epub 2009 Aug 22.


Background: A previous study found that consuming 5 or more cups of coffee per day was associated with increased incidence of heart failure (HF). We sought to evaluate this association in a larger population.

Methods: We measured coffee consumption using food frequency questionnaires among 37,315 men without history of myocardial infarction, diabetes, or HF. They were observed for HF hospitalization or mortality from January 1, 1998, until December 31, 2006, using record linkage to the Swedish inpatient and cause of death registries. Cox proportional hazards models adjusted for age, dietary, and demographic factors were used to calculate incidence rate ratios (RR) and 95% confidence intervals (CIs).

Results: For 9 years of follow-up, 784 men experienced an HF event. Compared to men who drank <or=1 cup of coffee per day (unadjusted rate 29.9 HF events/10,000 person-years), RR were 0.87 (95% CI 0.69-1.11, unadjusted rate 29.2/10,000 person-years) for 2 cups/d, 0.89 (95% CI 0.70-1.14, unadjusted rate 25.1/10,000 person-years) for 3 cups/d, 0.89 (95% CI 0.69-1.15, unadjusted rate 25.0/10,000 person-years) for 4 cups/d, and 0.89 (95% CI 0.69-1.15, unadjusted rate 18.1/10,000 person-years) for >or=5 cups/d (P for trend in RR = .61).

Conclusions: This study did not support the hypothesis that high coffee consumption is associated with increased rates of HF hospitalization or mortality.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Cause of Death / trends
  • Coffee / adverse effects*
  • Disease-Free Survival
  • Follow-Up Studies
  • Heart Failure / epidemiology*
  • Heart Failure / etiology
  • Hospitalization / trends*
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Prognosis
  • Prospective Studies
  • Risk Factors
  • Surveys and Questionnaires
  • Survival Rate / trends
  • Sweden / epidemiology
  • Time Factors


  • Coffee