Overexpression of cytochrome P450 4F2 in mice increases 20-hydroxyeicosatetraenoic acid production and arterial blood pressure

Kidney Int. 2009 Oct;76(8):913; author reply 913-4. doi: 10.1038/ki.2009.281.
No abstract available

Publication types

  • Letter
  • Comment

MeSH terms

  • Animals
  • Blood Pressure* / genetics
  • Cytochrome P-450 Enzyme System / genetics
  • Cytochrome P-450 Enzyme System / metabolism*
  • Cytochrome P450 Family 4
  • Disease Models, Animal
  • Humans
  • Hydroxyeicosatetraenoic Acids / metabolism*
  • Hypertension / enzymology*
  • Hypertension / genetics
  • Hypertension / physiopathology
  • Mice
  • Mice, Transgenic
  • Species Specificity
  • Up-Regulation

Substances

  • Hydroxyeicosatetraenoic Acids
  • 20-hydroxy-5,8,11,14-eicosatetraenoic acid
  • Cytochrome P-450 Enzyme System
  • Cytochrome P450 Family 4
  • CYP4F2 protein, human