Analysis of clarithromycin resistance and CagA status in Helicobacter pylori by use of feces from children in Thailand

J Clin Microbiol. 2009 Dec;47(12):4144-5. doi: 10.1128/JCM.00786-09. Epub 2009 Sep 30.

Abstract

The clarithromycin resistance and CagA status of Helicobacter pylori in Thai children were investigated using fecal samples. Of the 284 samples, H. pylori was detected in 120 samples, and the clarithromycin resistance rate was 29.2%. The cagA gene was detected in 59 samples, and only 6.8% of these samples contained the East Asian CagA type.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Antigens, Bacterial / genetics
  • Bacterial Proteins / genetics
  • Child
  • Child, Preschool
  • Clarithromycin / pharmacology*
  • Drug Resistance, Bacterial*
  • Feces / microbiology*
  • Female
  • Helicobacter pylori* / classification
  • Helicobacter pylori* / drug effects
  • Helicobacter pylori* / genetics
  • Helicobacter pylori* / isolation & purification
  • Humans
  • Infant
  • Male
  • Microbial Sensitivity Tests
  • Prevalence
  • Thailand / epidemiology

Substances

  • Anti-Bacterial Agents
  • Antigens, Bacterial
  • Bacterial Proteins
  • cagA protein, Helicobacter pylori
  • Clarithromycin