Cord blood transplantation for haematological malignancies: conditioning regimens, double cord transplant and infectious complications

Br J Haematol. 2009 Oct;147(2):207-16. doi: 10.1111/j.1365-2141.2009.07782.x.

Abstract

Growing evidence supports the efficacy of cord blood transplantation (CBT) to treat patients with haematological malignancies, and the number of CBTs is rapidly increasing. Herein, we review considerations regarding conditioning regimens for CBT, the impact of double unit transplantation on CBT outcomes, and data regarding infectious complications following CBT.

Publication types

  • Review

MeSH terms

  • Algorithms
  • Cord Blood Stem Cell Transplantation / adverse effects
  • Cord Blood Stem Cell Transplantation / methods*
  • Donor Selection / methods
  • Hematologic Neoplasms / therapy*
  • Humans
  • Opportunistic Infections / etiology*
  • Transplantation Conditioning / methods*
  • Whole-Body Irradiation / methods