Methods for analysis of crossover interference in Saccharomyces cerevisiae

Methods Mol Biol. 2009:557:35-53. doi: 10.1007/978-1-59745-527-5_4.


Interest in crossover interference in yeast has been spurred by the discovery and characterization of mutants that alter it as well as by the development and testing of models to explain it. This chapter describes methods for detecting and for measuring interference, with emphasis on those that exploit the ability to examine all four products of individual acts of meiosis.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Chromosomes, Fungal / metabolism
  • Crossing Over, Genetic / physiology*
  • Genetic Techniques*
  • Meiosis / genetics
  • Models, Genetic
  • Mutation / physiology
  • Organisms, Genetically Modified
  • Saccharomyces cerevisiae / genetics*