Congenital cytomegalovirus (CMV) epidemiology and awareness

J Clin Virol. 2009 Dec;46 Suppl 4:S6-10. doi: 10.1016/j.jcv.2009.09.002. Epub 2009 Oct 2.


This commentary highlights and discusses the implications of a number of recent studies that refine epidemiologic knowledge of CMV infection and assess awareness of congenital CMV among clinicians and the public. These studies highlight that: (1) congenital CMV results in a disease burden that is substantial and severe; (2) a high proportion of United States women of reproductive age are susceptible to CMV infection; (3) the majority of congenital CMV infections in the United States result from recurrent infections among pregnant women; (4) CMV seroprevalence and seroincidence are much higher among racial/ethnic minorities and persons of lower socioeconomic status (SES); (5) household transmission of CMV appears to be an important transmission route in the United States; (6) sexual transmission of CMV appears to be an important transmission route in some population sub-groups in the United States; (7) women have limited awareness and knowledge about congenital CMV; (8) most obstetrician/gynecologists do not counsel women about prevention of congenital CMV; (9) most women view CMV prevention messages positively.

MeSH terms

  • Antibodies, Viral / blood
  • Awareness
  • Cytomegalovirus Infections / congenital*
  • Cytomegalovirus Infections / diagnosis
  • Cytomegalovirus Infections / epidemiology*
  • Cytomegalovirus Infections / prevention & control
  • Female
  • Health Knowledge, Attitudes, Practice
  • Humans
  • Infectious Disease Transmission, Vertical / prevention & control
  • Patient Education as Topic
  • Pregnancy
  • Pregnancy Complications, Infectious / diagnosis
  • Pregnancy Complications, Infectious / epidemiology*
  • Pregnancy Complications, Infectious / prevention & control
  • Pregnancy Complications, Infectious / virology*
  • Prenatal Diagnosis
  • Risk Factors
  • Seroepidemiologic Studies
  • United States / epidemiology


  • Antibodies, Viral