Chemical and structural biology to direct the repurposing of sulindac

ChemMedChem. 2009 Nov;4(11):1793-5. doi: 10.1002/cmdc.200900384.

Authors

Jeffrey R Simard¹, Daniel Rauh

Affiliation

¹ Chemical Genomics Centre of the Max-Planck-Society, Dortmund, Germany.

PMID: 19802856
DOI: 10.1002/cmdc.200900384

No abstract available

MeSH terms

Adaptor Proteins, Signal Transducing / chemistry*
Adaptor Proteins, Signal Transducing / metabolism
Anti-Inflammatory Agents, Non-Steroidal / chemistry*
Binding Sites
Computer Simulation
Cyclooxygenase Inhibitors / chemistry
Dishevelled Proteins
Phosphoproteins / chemistry*
Phosphoproteins / metabolism
Prostaglandin-Endoperoxide Synthases / metabolism
Protein Structure, Tertiary
Signal Transduction
Sulindac / chemistry*
Wnt Proteins / metabolism

Substances

Adaptor Proteins, Signal Transducing
Anti-Inflammatory Agents, Non-Steroidal
Cyclooxygenase Inhibitors
Dishevelled Proteins
Phosphoproteins
Wnt Proteins
Sulindac
Prostaglandin-Endoperoxide Synthases