Low-energy distal radius fractures in middle-aged and elderly men and women--the burden of osteoporosis and fracture risk : A study of 1794 consecutive patients

Osteoporos Int. 2010 Jul;21(7):1257-67. doi: 10.1007/s00198-009-1068-x. Epub 2009 Oct 8.

Abstract

One third of 218 men and half of 1,576 women with low-energy distal radius fractures met the bone mineral density (BMD) criteria for osteoporosis treatment. A large proportion of patients with increased fracture risk did not have osteoporosis. Thus, all distal radius fracture patients >or=50 years should be referred to bone densitometry.

Introduction: Main objectives were to determine the prevalence of patients with a low-energy distal radius fracture in need of osteoporosis treatment according to existing guidelines using T-score <or= -2.0 or <or=-2.5 standard deviation (SD) and calculate their fracture risk.

Methods: A total of 218 men and 1,576 women >or=50 years were included. BMD was assessed by dual energy X-ray absorptiometry (DXA) at femoral neck, total hip, and lumbar spine (L2-L4). The WHO fracture risk assessment tool (FRAX(R)) was applied to calculate the 10-year fracture risk.

Results: T-scores <or=-2.0 and <or=-2.5 SD at femoral neck was found in 37.7% and 19.6% of men and 51.1% and 31.2% of women, respectively. The risk of hip fracture was 6.2% for men and 9.0% for women. The corresponding figures for patients with T-score <or=-2.0 SD were 11.6% and 14.5% and for T-score <or=-2.5 SD 16.3% and 18.2%, respectively. A large proportion of distal radius fracture patients with a high 10-year FRAX risk did not have osteoporosis.

Conclusions: Every second to every third fracture patient met the present BMD criteria for osteoporosis treatment. Because a large proportion of distal radius fracture patients did not have osteoporosis, treatment decisions should not be based on fracture risk assessment without bone densitometry. Thus, all distal radius fracture patients >or=50 years should be referred to bone densitometry, and if indicated, offered medical treatment.

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Absorptiometry, Photon
  • Aged
  • Aged, 80 and over
  • Bone Density
  • Bone Density Conservation Agents / therapeutic use
  • Female
  • Femur Neck / physiopathology
  • Hip Fractures / epidemiology
  • Hip Fractures / etiology
  • Hip Fractures / physiopathology
  • Hip Joint / physiopathology
  • Humans
  • Lumbar Vertebrae / physiopathology
  • Male
  • Middle Aged
  • Norway / epidemiology
  • Osteoporosis / complications
  • Osteoporosis / drug therapy
  • Osteoporosis / epidemiology
  • Osteoporosis, Postmenopausal / complications
  • Osteoporosis, Postmenopausal / drug therapy
  • Osteoporosis, Postmenopausal / epidemiology
  • Osteoporotic Fractures / epidemiology*
  • Osteoporotic Fractures / physiopathology
  • Radius Fractures / epidemiology*
  • Radius Fractures / etiology
  • Radius Fractures / physiopathology
  • Risk Assessment / methods

Substances

  • Bone Density Conservation Agents