A compiled and systematic reference map of nucleosome positions across the Saccharomyces cerevisiae genome

Genome Biol. 2009;10(10):R109. doi: 10.1186/gb-2009-10-10-r109. Epub 2009 Oct 8.


Nucleosomes have position-specific functions in controlling gene expression. A complete systematic genome-wide reference map of absolute and relative nucleosome positions is needed to minimize potential confusion when referring to the function of individual nucleosomes (or nucleosome-free regions) across datasets. We compiled six high-resolution genome-wide maps of Saccharomyces cerevisiae nucleosome positions from multiple labs and detection platforms, and report new insights. Data downloads, reference position assignment software, queries, and a visualization browser are available online http://atlas.bx.psu.edu/.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Databases, Genetic
  • Genome, Fungal / genetics*
  • Nucleosomes / genetics*
  • Reference Standards
  • Saccharomyces cerevisiae / genetics*
  • Sequence Analysis, DNA
  • Transcription Initiation Site


  • Nucleosomes