[Vestibular findings in patients with Vogt-Koyanagi-Harada syndrome]

Acta Otorrinolaringol Esp. 2009 Sep-Oct;60(5):305-10. doi: 10.1016/j.otorri.2009.05.004. Epub 2009 Sep 5.
[Article in Spanish]

Abstract

Objective: To identify and describe vestibular abnormalities in patients with Vogt-Koyanagi-Harada syndrome (VKH).

Materials and method: Prospective, cross-sectional, observational and descriptive study. Patients with VKH referred by an ophthalmological center, were interrogated and physically examined in search of signs of vestibular abnormalities, and if positive, they underwent videonystagmography, computerized dynamic posturography, tonal audiometry and tympanometry.

Results: Out of 21 patients with VKH, only 10 were included in the study due to presenting data of vestibular abnormalities (10/10 with vestibular symptoms and 9/10 with abnormalities in the physical exploration). The age average was 37.8 years. The videonystagmography was mainly abnormal in ocular saccades test (10/10). The posturography showed a higher alteration of the visual (4/10) and vestibular (4/10) afferents. A diagnosis of benign paroxysmal positional vertigo was mostly concluded (6/10). None presented abnormalities of the middle ear nor data of central pathology, 6/10 presented abnormalities in tonal audiometry.

Conclusions: Peripheral vestibular disorder is often present in the population with VKH.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Cross-Sectional Studies
  • Female
  • Humans
  • Male
  • Prospective Studies
  • Uveomeningoencephalitic Syndrome / physiopathology*
  • Vestibule, Labyrinth / physiopathology*