Cataract surgery in pseudoexfoliation syndrome

Curr Opin Ophthalmol. 2010 Jan;21(1):25-34. doi: 10.1097/ICU.0b013e328332f814.


Purpose of review: To discuss the preoperative, intraoperative and postoperative considerations and techniques for cataract surgery in pseudoexfoliation syndrome.

Recent findings: Pseudoexfoliation syndrome is a common disorder worldwide that has been linked to the lysyl oxidase-like-one (LOXL1) gene. Its identification in patients undergoing cataract surgery has become important in preventing complications through proper preoperative planning. The management of the small pupil found in pseudoexfoliation can be achieved using various pharmacological and mechanical techniques. There are now several devices available to support the weak zonules that commonly accompany pseudoexfoliation. Postoperatively, pseudoexfoliation patients need to be followed closely to monitor for complications such as intraocular pressure spikes, inflammation and intraocular lens dislocation.

Summary: With proper preoperative preparation, intraoperative use of appropriate adjunctive devices, and close postoperative follow-up, favorable outcomes can be achieved in cataract surgery in pseudoexfoliation syndrome.

Publication types

  • Review

MeSH terms

  • Cataract / complications*
  • Cataract Extraction*
  • Exfoliation Syndrome / complications*
  • Humans
  • Postoperative Care
  • Preoperative Care