Early response to family-based treatment for adolescent anorexia nervosa

Int J Eat Disord. 2010 Nov 1;43(7):659-62. doi: 10.1002/eat.20764.


Objective: The purpose of this study was to determine if early weight gain predicted remission at the end of treatment in a clinic sample of adolescents with anorexia nervosa (AN).

Method: Sixty five adolescents with AN (mean age = 14.9 years, SD = 2.1), from two sites (Chicago n = 45; Columbia n = 20) received a course of manualized family-based treatment (FBT). Response to treatment was assessed using percent ideal body weight (IBW) with remission defined as having achieved ≥ 95% IBW at end of treatment (Session 20).

Results: Receiver operating characteristic analyses showed that a gain of at least 2.88% in ideal body weight by Session 4 best predicted remission at end of treatment (AUC = 0.674; p = 0.024).

Discussion: Results suggest that adolescents with AN, receiving FBT, who do not show early weight gain are unlikely to remit at end of treatment.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adolescent
  • Anorexia Nervosa / diagnosis
  • Anorexia Nervosa / psychology*
  • Anorexia Nervosa / therapy*
  • Body Weight
  • Chicago
  • Family Therapy / methods*
  • Female
  • Humans
  • Male
  • New York
  • ROC Curve
  • Time Factors
  • Treatment Outcome
  • Weight Gain / physiology*