Kyphoplasty for chronic painful osteoporotic vertebral compression fractures via unipedicular versus bipedicular approachment: a comparative study in early stage

Injury. 2010 Apr;41(4):356-9. doi: 10.1016/j.injury.2009.09.021. Epub 2009 Oct 9.


Background: Osteoporotic compression fractures (OVCFs) commonly occur in aged people, and as much as one-third of these fractures progress to chronic pain. Kyphoplasty (KP) is proved to be efficacious for pain relief and vertebral height restoration in chronic OVCFs, but there is still no data available about the clinical and radiographical outcomes compared by unipedicular and bipedicular KP in treating chronic painful OVCFs.

Purpose: To assess the clinical and radiographical outcomes in treating chronic painful OVCFs compared by unipedicular and bipedicular KP.

Methods: Fifty-eight patients with a total of sixty-six chronic painful OVCFs were enroled in our study. They were randomly allocated into two groups: group I (n=33) was treated with unipedicular KP and group II (n=25) with bipedicular KP. The operation times for each group were recorded and compared. Preoperative and postoperative of visual analogue scores (VAS) and oswestry disability index (ODI) scores were compared 2 weeks after surgery within each group and between groups. The radiographic outcomes were evaluated by the restoration rate (RR) in the most compressed point of the vertebral bodies.

Results: Significant improvement on the VAS, ODI scores and RR was noted in each group (p<0.001), and there is no significant difference existing in clinical outcomes between the two groups. The mean operation time for each vertebra in group I was significantly shorter than in group II (p<0.001). But the RR in group II was higher than in group I (p=0.041).

Conclusion: Both unipedicular kyphoplasty and bipedicular kyphoplasty can achieve satisfactory clinical and radiographic outcomes in treating the chronic painful OVCFs and the operation time is shorter in unipedicular kyphoplasty. However, the bipedicular kyphoplasty is more efficacious in height restoration.

Publication types

  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Aged
  • Back Pain / surgery
  • Bone Cements / therapeutic use
  • Chronic Disease
  • Disability Evaluation
  • Female
  • Fractures, Compression / diagnostic imaging
  • Fractures, Compression / etiology
  • Fractures, Compression / surgery*
  • Humans
  • Middle Aged
  • Osteoporosis / complications*
  • Polymethyl Methacrylate / therapeutic use
  • Radiography
  • Spinal Fractures / diagnostic imaging
  • Spinal Fractures / etiology
  • Spinal Fractures / surgery*
  • Treatment Outcome
  • Vertebroplasty / methods*


  • Bone Cements
  • Polymethyl Methacrylate