VIGS--genomics goes functional

Trends Plant Sci. 2010 Jan;15(1):1-4. doi: 10.1016/j.tplants.2009.09.002. Epub 2009 Oct 8.


Genome and EST sequencing projects generate a wealth of sequence information for agronomically and phylogenetically important plant species of which the majority is difficult to subject to functional genomics. Virus-induced gene silencing (VIGS) provides a powerful tool to enable gene functional analysis for species not amenable to stable genetic transformation. Recent approaches allow the use of VIGS as a high throughput method that will exploit the potential of genome and transcriptome projects further.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Gene Silencing*
  • Genome, Plant*
  • Genomics / methods*
  • Phylogeny
  • Viruses / genetics*