Evaluating the antifertility potential of an aqueous extract from Cassia fistula seeds in male rats

Fertil Steril. 2010 Mar 15;93(5):1706-10. doi: 10.1016/j.fertnstert.2009.09.001. Epub 2009 Oct 12.

Abstract

Cassia fistula suppresses fertility in male rats. Withdrawal of extract restored all the altered parameters, including organ weights, fertility, circulatory level of hormones and tissue biochemistry, to control levels after 120 days.

MeSH terms

  • Animals
  • Cassia*
  • Contraceptive Agents, Male / pharmacology*
  • Dose-Response Relationship, Drug
  • Female
  • Fertility / drug effects*
  • Litter Size / drug effects
  • Male
  • Organ Size / drug effects
  • Plant Extracts / pharmacology*
  • Pregnancy
  • Rats
  • Rats, Wistar
  • Seeds
  • Spermatogenesis / drug effects
  • Testis / drug effects*
  • Testis / metabolism
  • Testis / pathology
  • Testosterone / blood
  • Time Factors

Substances

  • Contraceptive Agents, Male
  • Plant Extracts
  • Testosterone