Plasma membrane repair in plants

Trends Plant Sci. 2009 Dec;14(12):645-52. doi: 10.1016/j.tplants.2009.09.004. Epub 2009 Oct 12.


Resealing is the membrane-repair process that enables cells to survive disruption, preventing the loss of irreplaceable cell types and eliminating the cost of replacing injured cells. Given that failure in the resealing process in animal cells causes diverse types of muscular dystrophy, plasma membrane repair has been extensively studied in these systems. Animal proteins with Ca(2+)-binding domains such as synaptotagmins and dysferlin mediate Ca(2+)-dependent exocytosis to repair plasma membranes after mechanical damage. Until recently, no components or proof for membrane repair mechanisms have been discovered in plants. However, Arabidopsis SYT1 is now the first plant synaptotagmin demonstrated to participate in Ca(2+)-dependent repair of membranes. This suggests a conservation of membrane repair mechanisms between animal and plant cells.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Arabidopsis / metabolism
  • Arabidopsis Proteins / metabolism*
  • Calcium / metabolism
  • Cell Membrane / metabolism
  • Membrane Fusion*
  • Models, Biological
  • SNARE Proteins / metabolism*
  • Synaptotagmins / metabolism*


  • Arabidopsis Proteins
  • SNARE Proteins
  • Synaptotagmins
  • Calcium