Outcome domains for studies of acute and chronic gout

J Rheumatol. 2009 Oct;36(10):2342-5. doi: 10.3899/jrheum.090370.

Abstract

Discussion and voting at OMERACT 9 confirmed 5 essential domains for outcomes of acute gout: pain, joint swelling, joint tenderness, patient global assessment and activity limitations. For studies in chronic gout 7 essential domains are: serum urate, acute gout attacks, tophus burden, health-related quality of life, activity limitations, pain, and patient global assessment. Implications of patient perspectives, discretionary domains for specific studies, measurement instruments and a possible responder index are under study.

MeSH terms

  • Acute Disease
  • Arthralgia / physiopathology
  • Chronic Disease
  • Consensus*
  • Disability Evaluation
  • Gout / diagnosis*
  • Gout / physiopathology
  • Gout / psychology
  • Humans
  • Outcome Assessment, Health Care / standards*
  • Quality of Life
  • Severity of Illness Index*
  • Uric Acid / blood

Substances

  • Uric Acid