Continuous positive airway pressure (CPAP) with prongs is the ventilatory support most used in newborns. Nasal injuries are complications that may arise due to the prolonged use of this device. This study aimed to determine the frequency of nasal injuries in newborns through the use of continuous positive airway pressure with prongs. A convenience sample composed of hospitalized newborns using prongs for more than two days was used. Data were collected through a structured form. Lesions were observed in all newborns, which were classified as: mild (79.6%), moderate (19.7%) and severe (0.7%). The conclusion is that the use of prongs for more than two days represents a risk factor for the lesions to develop.