Prolonged myoclonus after a single bolus dose of propofol

Anaesthesia. 2009 Nov;64(11):1254-7. doi: 10.1111/j.1365-2044.2009.06035.x.


Propofol is a commonly used anaesthetic agent and is rarely associated with seizure-like phenomena. This case report presents a young woman with seizure-like phenomena lasting more than 4 weeks after a single dose of propofol. The underlying pathophysiology of this condition is poorly understood but a psychological component is possible in this case.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anesthetics, Intravenous / adverse effects*
  • Female
  • Humans
  • Myoclonus / chemically induced*
  • Postoperative Complications / chemically induced*
  • Propofol / adverse effects*


  • Anesthetics, Intravenous
  • Propofol