Uses of misoprostol in obstetrics and gynecology

Rev Obstet Gynecol. Summer 2009;2(3):159-68.


Misoprostol is a synthetic prostaglandin E(1) analogue that is used off-label for a variety of indications in the practice of obstetrics and gynecology, including medication abortion, medical management of miscarriage, induction of labor, cervical ripening before surgical procedures, and the treatment of postpartum hemorrhage. Due to its wide-ranging applications in reproductive health, misoprostol is on the World Health Organization Model List of Essential Medicines. This article briefly reviews the varied uses of misoprostol in obstetrics and gynecology.

Keywords: Cervical ripening; Hysteroscopy; Induced abortion; Induction of labor; Misoprostol; Postpartum hemorrhage.