Molecular Evolution of the mtDNA Encoded rps3 Gene Among Filamentous Ascomycetes Fungi With an Emphasis on the Ophiostomatoid Fungi

J Mol Evol. 2009 Oct;69(4):372-85. doi: 10.1007/s00239-009-9291-9. Epub 2009 Oct 14.


The mitochondrial ribosomal protein S3 (rps3) gene within the fungi is extremely diverse in location and organization, some versions of this gene have been incorporated into a group I intron, others appear to have gained large insertions, microsatellite expansions, or have been invaded by homing endonucleases. Among the ascomycetes fungi the group I intron encoded version of rps3 appears to have a rather complex evolutionary history including first the acquisition of rps3 by a group I intron (mL2449), the loss of the mL2499 intron and the establishment of rps3 as a free-standing gene, and the eventual loss of the intron derived version of rps3.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Codon / genetics
  • DNA, Mitochondrial / genetics*
  • Evolution, Molecular*
  • Genes, Fungal / genetics*
  • Genes, Mitochondrial / genetics
  • Genetic Variation
  • Introns / genetics
  • Ophiostomatales / genetics*
  • Phylogeny
  • Ribosomal Proteins / chemistry
  • Ribosomal Proteins / genetics*
  • Sequence Homology, Nucleic Acid


  • Codon
  • DNA, Mitochondrial
  • Ribosomal Proteins
  • ribosomal protein S3