Retinal angiomatous proliferation (RAP) in a 42-year-old woman with syphilitic retinitis

Ocul Immunol Inflamm. Sep-Oct 2009;17(5):361-3. doi: 10.3109/09273940903090189.


Purpose: To present a case of a young individual with retinal angiomatous proliferation (RAP) on the background of syphilitic retinitis.

Methods/design: Interventional case report.

Results: A 42-year-old Caucasian with confirmed diagnosis of syphilitic retinitis in both eyes revealed the existence of RAP in the RE that responded well to one session of intravitreal triamcinolone acetonide and photodynamic therapy.

Conclusion: To the best of our knowledge this is the first report of RAP in such a young individual. Further research is required in order to examine the possibility of inflammation playing a role in the pathophysiology of RAP.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Angiomatosis / complications*
  • Angiomatosis / diagnosis
  • Angiomatosis / drug therapy
  • Coloring Agents
  • Female
  • Fluorescein Angiography
  • Fundus Oculi
  • Glucocorticoids / administration & dosage
  • Humans
  • Indocyanine Green
  • Photochemotherapy
  • Retinal Diseases / complications*
  • Retinal Diseases / diagnosis
  • Retinal Diseases / drug therapy
  • Retinitis / complications*
  • Retinitis / microbiology*
  • Syphilis*
  • Tomography, Optical Coherence
  • Triamcinolone Acetonide / administration & dosage
  • Vitreous Body


  • Coloring Agents
  • Glucocorticoids
  • Triamcinolone Acetonide
  • Indocyanine Green