Prevalence of dementia and cognitive impairment in Southeastern Spain: the Ariadna study

Acta Neurol Scand. 2009 Nov;120(5):300-7. doi: 10.1111/j.1600-0404.2009.01283.x.


Objectives: To estimate the prevalence of amnestic mild cognitive impairment (aMCI), cognitive impairment, no dementia (CIND) and dementia in a general elderly population and to examine the associated socio-demographic factors.

Methods: The Ariadna study is a population-based cross-sectional study of cognitive function involving 1074 individuals aged 65-96 years from the Murcia Region of southeastern Spain. Prevalence, adjusted odds ratio (OR) and 95% confidence intervals (CI) were calculated.

Results: The overall prevalence was 8.7% (95% CI 7.1-10.5) for aMCI, 14.5% (95% CI 12.4-16.8) for CIND and 5.5% (95% CI 4.3-7.1) for dementia. Dementia was associated with age (OR 1.13 95% CI 1.09-1.18 for a 1-year increase in age). Illiterate subjects were more likely to present aMCI (OR 2.59; 95% CI 1.09-6.14) and dementia (OR 4.09; 95% CI 1.28-13.08) than subjects with secondary or higher education. Rural area residents (OR 2.13, 95% CI 1.07-4.24) and women (OR 1.53, 95% CI 1.06-2.22) were more likely to have CIND.

Conclusion: The prevalence of dementia was low, despite a high prevalence of aMCI and CIND. Dementia was strongly associated with age and education. CIND was associated with living in a rural area and with female sex, while aMCI was associated with illiteracy.

MeSH terms

  • Age Factors
  • Aged
  • Aged, 80 and over
  • Analysis of Variance
  • Brain / pathology*
  • Cognition Disorders / diagnosis
  • Cognition Disorders / epidemiology*
  • Cross-Sectional Studies
  • Dementia / diagnosis
  • Dementia / epidemiology*
  • Educational Status
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Neurologic Examination
  • Neuropsychological Tests
  • Odds Ratio
  • Prevalence
  • Rural Population
  • Sex Factors
  • Spain / epidemiology
  • Urban Population