Gut immune balance is as easy as S-F-B

Immunity. 2009 Oct 16;31(4):536-8. doi: 10.1016/j.immuni.2009.09.005.

Abstract

Microbes appear to modulate homeostatic plasticity of T helper and T regulatory cells. In this issue of Immunity, Gaboriau-Routhiau et al. (2009) now reveal that segmented filamentous bacteria uniquely coordinate the intestinal T cell profile. The potential implications of this process to various immune functions are discussed.

Publication types

  • Comment

MeSH terms

  • Animals
  • Bacteria / immunology
  • CD4-Positive T-Lymphocytes / immunology*
  • CD4-Positive T-Lymphocytes / metabolism
  • CD4-Positive T-Lymphocytes / microbiology
  • Cytokines / immunology
  • Cytokines / metabolism
  • Humans
  • Intestinal Mucosa / metabolism
  • Intestines / immunology*
  • Intestines / microbiology*
  • T-Lymphocytes, Helper-Inducer / immunology*
  • T-Lymphocytes, Helper-Inducer / metabolism
  • T-Lymphocytes, Helper-Inducer / microbiology
  • T-Lymphocytes, Regulatory / immunology*
  • T-Lymphocytes, Regulatory / metabolism
  • T-Lymphocytes, Regulatory / microbiology

Substances

  • Cytokines