Surgical management of well-differentiated thyroid cancer: state of the art

Surg Clin North Am. 2009 Oct;89(5):1171-91. doi: 10.1016/j.suc.2009.06.013.


Nonmedullary well-differentiated thyroid cancer (WDTC) comprises a group of tumors including papillary thyroid carcinoma (PTC) and follicular thyroid carcinoma (FTC), with Hürthle cell carcinoma being a subtype of follicular carcinoma. This article reviews the epidemiology, pathogenesis, preoperative and diagnostic evaluation, imaging, and staging of WDTC. Different approaches to therapy and follow-up care are discussed. The prognosis for WDTC remains good and most patients can expect to be cured of their disease.

Publication types

  • Review

MeSH terms

  • Humans
  • Lymph Node Excision
  • Lymphatic Metastasis
  • Neoplasm Recurrence, Local
  • Neoplasm, Residual
  • Population Surveillance
  • Thyroid Neoplasms / pathology
  • Thyroid Neoplasms / surgery*
  • Thyroidectomy / methods*