Hwp1 and related adhesins contribute to both mating and biofilm formation in Candida albicans

Iuliana V Ene; Richard J Bennett

doi:10.1128/EC.00245-09

Hwp1 and related adhesins contribute to both mating and biofilm formation in Candida albicans

Eukaryot Cell. 2009 Dec;8(12):1909-13. doi: 10.1128/EC.00245-09. Epub 2009 Oct 16.

Authors

Iuliana V Ene¹, Richard J Bennett

Affiliation

¹ Department of Molecular Microbiology and Immunology, Brown University, Providence, RI 02912, USA.

Abstract

Candida albicans Hwp1, Hwp2, and Rbt1 are related cell wall proteins expressed during the programs of sexual differentiation and filamentous growth. In this study, we compare strains lacking either single factors or a combination of these genes, and we demonstrate distinct but overlapping roles in mating and biofilm formation.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Biofilms / growth & development*
Candida albicans / cytology
Candida albicans / genetics*
Candida albicans / physiology*
Cell Membrane / metabolism
Fungal Proteins / metabolism*
Genes, Mating Type, Fungal*
Membrane Glycoproteins / metabolism*

Substances

Fungal Proteins
HWP1 protein, Candida albicans
Membrane Glycoproteins