Hwp1 and related adhesins contribute to both mating and biofilm formation in Candida albicans

Eukaryot Cell. 2009 Dec;8(12):1909-13. doi: 10.1128/EC.00245-09. Epub 2009 Oct 16.


Candida albicans Hwp1, Hwp2, and Rbt1 are related cell wall proteins expressed during the programs of sexual differentiation and filamentous growth. In this study, we compare strains lacking either single factors or a combination of these genes, and we demonstrate distinct but overlapping roles in mating and biofilm formation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biofilms / growth & development*
  • Candida albicans / cytology
  • Candida albicans / genetics*
  • Candida albicans / physiology*
  • Cell Membrane / metabolism
  • Fungal Proteins / metabolism*
  • Genes, Mating Type, Fungal*
  • Membrane Glycoproteins / metabolism*


  • Fungal Proteins
  • HWP1 protein, Candida albicans
  • Membrane Glycoproteins