The fate of chromosomal aberrations in 137Cs-exposed individuals in the Goiânia radiation accident

Health Phys. 1991 Jan;60(1):67-70. doi: 10.1097/00004032-199101000-00010.

Abstract

Following the Goiânia radiation accident, lymphocytes from 110 exposed or potentially exposed individuals were analyzed for the frequencies of chromosomal aberrations (dicentrics and centric rings) to estimate absorbed radiation dose. Dose estimates for 21 subjects exceeded 1.0 Gy, and for eight subjects they exceeded 4.0 Gy. Four of the subjects died. After the emergency period, a cytogenetic follow-up of 10 of the highest exposed patients was started. The results suggest that the average disappearance half-time of lymphocytes containing dicentric and centric rings was 130 d, which is shorter than the usually accepted value of 3 y reported in the literature.

MeSH terms

  • Accidents*
  • Adolescent
  • Adult
  • Brazil
  • Cesium Radioisotopes*
  • Chromosome Aberrations*
  • Environmental Exposure*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Radiation Dosage
  • Radioisotope Teletherapy / instrumentation
  • Radiometry / methods

Substances

  • Cesium Radioisotopes