Abstract
Immune dysfunction, a well-established feature of neuroinflammatory disease, is increasingly recognized in neurodegenerative conditions. Its role is emerging as an early and active participant in neuropathology. Inflammation could be modified, with disease-slowing effects, by targeted interventions; it is also readily detectable and could serve as a source of valuable biomarkers.
MeSH terms
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Animals
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Biomarkers / metabolism
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Brain / immunology
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Brain / physiopathology
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Humans
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Immunity, Innate
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Inflammation / immunology*
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Inflammation / physiopathology*
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Microglia / physiology
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Neurodegenerative Diseases / diagnosis
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Neurodegenerative Diseases / immunology*
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Neurodegenerative Diseases / physiopathology*
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Neuroimmunomodulation / physiology*
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Spinal Cord / immunology
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Spinal Cord / physiology