Cryptogenetic intestinal angiodysplasia and elderly aortic stenosis: Heyde's syndrome? A case report

Chir Ital. Jul-Aug 2009;61(4):497-501.


Gastrointestinal haemorrhage is extremely frequent, but in some cases the aetiology may remain unknown. Haemorrhage from the small bowel especially can create important diagnostic problems. We report the case of a patient admitted to hospital with intestinal bleeding in an ileal site in association with aortic stenosis. Enteric angiodysplasia is a frequent pathology in the surgery of the gastrointestinal tract. Recognizing bleeding lesions in the small intestine can be really difficult. Concerning the case reported here, the most probable diagnostic hypothesis is Heyde's syndrome, which is characterised by valvular aortic stenosis together with gastrointestinal bleeding due to cryptogenetic angiodysplasias. The choice to be made in the therapeutic management of angiodysplasia is still a debatable issue and should be suited to the patient's clinical state and the site and extent of the bleeding. In the literature the link between aortic valvular stenosis and intestinal angiodysplasia is unclear. The physiopathological relationship between the two entities is still mysterious.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Angiodysplasia / complications*
  • Angiodysplasia / diagnosis
  • Aortic Valve Stenosis / complications*
  • Aortic Valve Stenosis / diagnosis
  • Female
  • Gastrointestinal Hemorrhage / etiology*
  • Humans
  • Ileal Diseases / complications*
  • Ileal Diseases / diagnosis
  • Syndrome