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Review
. 2010 Jan 14;115(2):168-86.
doi: 10.1182/blood-2009-06-225565. Epub 2009 Oct 21.

International Consensus Report on the Investigation and Management of Primary Immune Thrombocytopenia

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Review

International Consensus Report on the Investigation and Management of Primary Immune Thrombocytopenia

Drew Provan et al. Blood. .

Abstract

Previously published guidelines for the diagnosis and management of primary immune thrombocytopenia (ITP) require updating largely due to the introduction of new classes of therapeutic agents, and a greater understanding of the disease pathophysiology. However, treatment-related decisions still remain principally dependent on clinical expertise or patient preference rather than high-quality clinical trial evidence. This consensus document aims to report on new data and provide consensus-based recommendations relating to diagnosis and treatment of ITP in adults, in children, and during pregnancy. The inclusion of summary tables within this document, supported by information tables in the online appendices, is intended to aid in clinical decision making.

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