Molecular biology: Slip sliding on DNA

Nature. 2009 Oct 22;461(7267):1067-8. doi: 10.1038/4611067a.

Abstract

Dedicated binding proteins stabilize single-stranded DNA, protecting it from breakage and distortion. Once thought to form inert complexes with DNA, such proteins are now shown to be remarkably mobile.

Publication types

  • News
  • Comment

MeSH terms

  • DNA, Single-Stranded / chemistry
  • DNA, Single-Stranded / metabolism*
  • DNA-Binding Proteins / metabolism*
  • Diffusion*
  • Escherichia coli
  • Escherichia coli Proteins / metabolism*
  • Fluorescence Resonance Energy Transfer
  • Movement*
  • Nucleic Acid Conformation
  • Rec A Recombinases / chemistry*
  • Rec A Recombinases / metabolism*

Substances

  • DNA, Single-Stranded
  • DNA-Binding Proteins
  • Escherichia coli Proteins
  • SSB protein, E coli
  • Rec A Recombinases