Endoderm-specific Expression of the Drosophila mex1 Gene

Dev Biol. 1991 Jan;143(1):206-11. doi: 10.1016/0012-1606(91)90068-e.

Abstract

The Drosophila mex1 gene is one of several genes clustered within a 10-kb interval of polytene region 71CD that includes the ecdysone-regulated Eip28/29 gene. mex1 is expressed in several developmental stages, with gene transcripts accumulating initially in 9- to 12-hr embryos. During embryogenesis, mex1 exhibits an endoderm-specific pattern of expression. mex1 transcripts are first detected in the anterior and posterior midgut primordia of stage 12 embryos; subsequently, mex1 mRNA accumulates solely in the differentiating embryonic midgut. DNA sequence analysis reveals that the mex1 gene encodes an unusual cysteine-rich polypeptide.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Drosophila / embryology
  • Drosophila / genetics*
  • Endoderm / metabolism*
  • Gene Expression Regulation*
  • Molecular Sequence Data
  • Multigene Family
  • Nucleic Acid Hybridization
  • Organ Specificity / genetics
  • Restriction Mapping
  • Transcription, Genetic

Associated data

  • GENBANK/M63626
  • GENBANK/M65127
  • GENBANK/M65223
  • GENBANK/M65224
  • GENBANK/M65235
  • GENBANK/S60919
  • GENBANK/S60920
  • GENBANK/S89458
  • GENBANK/X58286
  • GENBANK/X59082